Genetic Susceptibility to Engage in Criminal Acts ?
نویسندگان
چکیده
Candidate genes are specific genes that contribute among many others to an increased risk of engaging in antisocial behaviour. They are usually selected on the basis of information about the neurobiological bases of behaviour and personality traits. Association studies examine whether one allele, or variant, of a candidate gene occurs more often in individuals who display antisocial behaviour than in some control comparison group. In case-control studies, researchers compare the frequencies of alleles in individuals who engage in antisocial behaviour and in unrelated, unaffected controls who have been matched on age, sex and ethnicity (Burmeister 1999). In family-based studies, such as the transmission disequilibrium test (TDT) and haplotype relative risk (HRR) method, researchers examine which alleles or combinations of genes (haplotypes) are transmitted from parents to affected offspring (Burmeister 1999).
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